Vol. 5, Issue 2, Part A (2023)

Recent advances in medicine have made it possible to successfully treat numerous disorders through surgical procedures, which frequently need the use of general anaesthetic. There is a rising interest in the CNS (central nervous system) issues related to anaesthetics, and concerns about the safety of general anaesthetic are on the rise as their usage becomes more commonplace. Recent years have seen a wealth of research pointing to the involvement of blood-brain-barrier (BBB) dysfunction and neurological inflammation in the emergence of CNS problems in the wake of anaesthesia. More research is needed to determine whether or not general anaesthesia causes BBB failure and neuroinflammation, and whether or not this interaction might be an option for treatment for CNS problems.