Vol. 6, Issue 1, Part A (2024)

Background: Endotracheal intubation was done to maintain airway patency in patients undergoing general anaesthesia. Endotracheal tube intubation might cause complications like sore throat, cough and horseness of voice. These all due to irritation and inflammation of airway as a result of trauma. This study is to compare 0.1% triamcinolons acetonide paste and 2% lignocaine gel for prophylaxis against intubation related post-operative pharyngo laryngeal complications.
Materials and Methods: A prospective, randomised, interventional study was conducted, over 50 ASA grade 1, 2 and 3, aged 18 to 60 years patients posted in general surgery, Neuro surgery, orthopaedic surgery and plastic surgery under general anaesthesia from December 2020 to November 2022 Prior to induction patients were randomly distributed in two groups: Group TA, triamcinolone acetonide paste and Group L, lignocaine hydrochloride gel. Data were analysed using SPSS software 22.0. A probability value of less ≤ 0.05 is considered statistically significant.
Results: General characteristics of the subjects included age, gender, ASA grade between 2 groups show no statistically significant difference. Triamcinone acetonide paste 0.1% was effective than lignocaine 2% gel in preventing and reducing the incidence of post-operative pharyngolaryngeal complications in first 24 hours post extubation. 
Conclusion: 0.1% triamcinolone acetonide paste was better anti-inflammatory and hemodynamic effect cause less postoperative pharyngolaryngeal complications.