Vol. 6, Issue 1, Part A (2024)

The semi-synthetic opioid nalbuphine has drawn interest due to its analgesic qualities; however, further research is needed to determine how it specifically affects hemodynamics during ear, nose, and throat (ENT) procedures. In order to comprehend the complex hemodynamic effects of nalbuphine during ENT procedures, this thorough review attempts to methodically analyse the body of literature currently in publication. During ENT procedures, nalbuphine shows potential as an analgesic medication with typically stable hemodynamic characteristics. However, a cautious interpretation is required due to the heterogeneity in study designs and outcomes. The study emphasises the necessity of standardising procedures and doing additional research to clarify patient-specific factors and guarantee the best possible use of nalbuphine in improving ENT patients' overall perioperative care.